Magazine Grid will help a lot as it is a ultramodern CSS-Framework which comes with common magazine design elements such as pagination, gutters and of course basic grid, built specifically for iPad.
The framework uses HTML5 elements for structuring the magazine pages. Simply, an <article>
element wraps up your page and <section>
s define the portions of content.
Magazine Grid weights only 4kb and has a fallback style for devices with smaller screens.
Compatibility: iPad
Website: http://asidemag.com/grid/