Streamie is a full web-based realtime Twitter client that runs in your web browser. New tweets will appear in your timeline immediately when someone posts them to Twitter.
It has different menus for displaying mentions, direct messages, favorites or retweets. And, as expected, you can send tweets easily.
A number of options help customizing the application like message filtering, display settings and enabling geolocation.
The application is fully Ajaxed + uses nodeJS, less.js, require.js and Socket.IO which can be a good way of getting experienced in these “getting popular” resources.
Requirements: nodeJS
Compatibility: All Major Browsers
Website: http://streamie.org/
Download: https://github.com/cramforce/streamie